Chemical attachment of an ester to the creatine molecule makes it incredibly lipophilic, or fat penetrating, allowing it to quickly and efficiently pass right through the lipid membranes of the gut and directly into the bloodstream for direct transport to your muscles. But one more thing - before creatine can go from the bloodstream to the muscle cells, it must once again face the same lipid membranes that it encountered in the gut. Now you understand why you absorb so little regular creatine. This is why Creatine Ethyl Ester HCL works much better than Krealklyn, which just buffers acid in the stomach to help Creatine get out of gut without breakdown but does not help with bloodstream to muscle cell transport.